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In the presence of oxygen, NFK is synthesised enzymatically by indoleamine 2,3-dioxygenase (IDO), which has been found in human lenses (105), or through tryptophan photolysis following in vitro exposure to UV light (106)

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Claims (4) Applications Claiming Priority (3) Related Parent Applications (2) Publications (2) Family ID=6331195 Family Applications (2) Family Applications Before (1) Country Status (8) Cited By (1) Families Citing this family (38) Citations (1) Family Cites Families (5) 1987 1987-07-09 DE DE19873722647 patent/DE3722647A1/en not_active Ceased 1988 1988-07-08 AU AU19944/88A patent/AU1994488A/en not_active Abandoned 1988-07-08 JP JP63505693A patent/JP2851289B2/en not_active Expired - Lifetime 1988-07-08 EP EP88905695A patent/EP0327612B1/en not_active Expired - Lifetime 1988-07-08 AT AT94108938T patent/ATE188968T1/en not_active IP Right Cessation 1988-07-08 EP EP94108938A patent/EP0655460B1/en not_active Expired - Lifetime 1988-07-08 AT AT88905695T patent/ATE121942T1/en not_active IP Right Cessation 1988-07-08 WO PCT/DE1988/000427 patent/WO1989000427A1/en not_active Ceased 1996 1996-07-22 LV LV960291A patent/LV5793B4/en unknown 1997 1997-06-05 HK HK74697A patent/HK74697A/en not_active IP Right Cessation 1998 1998-07-22 JP JP10206738A patent/JPH11106349A/en active Pending 1998-07-22 JP JP10206743A patent/JPH11147836A/en active Pending

Homocysteine, a nonprotein -amino acid, has been associated with high levels of oxidative stress (246)