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This combination has the additional benefits of increasing growth hormone production, helping to eliminate ammonia in those suffering from liver disease, decreasing blood pressure by increasing NO production, and improving carbohydrate metabolism in those with diabetes mellitus

If there is clinical improvement and if a reticulocyte response is observed, the same amount may be given on alternate days for seven doses, then every three to four days for another two to three weeks

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The longer the condition goes untreated, the higher the chance of permanent damage. Vitamin B12 deficiency is usually treated with injections of vitamin B12