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Early-phase clinical trials in neurodegenerative diseases have shown favorable pharmacokinetics and therapeutic potential, suggesting feasibility for adaptation in POCD contexts

OMalley GF, Mizrahi F, Giraldo P, OMalley RN, Rollins D, Wilkins D

Harris IS, DeNicola GM (2020) The complex interplay between antioxidants and ROS in cancer

Similarly, 18 F-DOPA PET-guided, dose-escalated, hypofractionated proton beam therapy has shown potential survival benefits with manageable adverse effects, 343 warranting further investigation in phase 2 trials (NCT05781321)
