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Sleeve gastrectomy is a procedure in which 7085% of the stomach is removed, resulting in a reduction in gastric reservoir size [51,52] and accelerated nutrient transit time, thus decreasing the absorption of nutrients [52]

Illustrating the complexity of the events that should be involved, for the counteracted effects of insulin-over dose [62], this can be the recovery of both insulin pathways (i.e., prominent counteraction of calcification of liver blood vessels [62] requires both insulin pathways inhibited [270,271])