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Resveratrol: a potential therapeutic natural polyphenol for neurodegenerative diseases associated with mitochondrial dysfunction

Competitive cell proliferation assays To assess the effect of CRISPR/ Cas9 -mediated gene targeting on cell proliferation, Cas9 -expressing cells were transduced with sgRNA/IRFP670 expression vectors and IRFP670-positive cells were monitored at regular intervals by flow cytometry using an IntelliCyt IQueScreener Plus (BioScience, Sartorius Group, Germany)

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