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In the control rats with a large lesion area and at the border of bone tissue and muscle, there was significant edema and no reaction of periosteum for mesenchymal stem cells (i.e., on post-operative day 2) (Figure 14)

After 1 month of treatment in pernicious anemia patients, the once weekly dosing of 500 mcg B12 intranasal gel resulted in a statistically significant increase in B12 levels when compared to a once monthly 100 mcg IM dose

A deficiency in vitamin B12 can show up in ways that are easy to dismiss as just stress or a busy schedule

However, material properties, such as elastic modulus and stress, do not recover to the same extent during the same time span 20,23,24