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[20] [21] Proton pump inhibitors (PPIs) such as omeprazole can reduce B12 absorption and may cause digestive upset

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B12 deficiency upregulates lipogenesis in mature human WAT To validate the evidence of low B12 effect on lipogenesis in the Chub-S7 cells and primary Sc adipocytes, gene expression was further investigated in ScWAT and OmWAT derived from pregnant women with sufficient and deficient levels of B12

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