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Furthermore, it alters the nucleic acid composition by reacting selectively with deoxyguanosine [43]
Other proteins known to bind IGF-1 include ten IGFBP-related proteins (IGFBP-rPs), albeit with lower affinities than the IGFBPs

We, therefore, selected a rare clinical model (secondary hypogonadism due to isolated LH deficiency), in which we may observe LH and testosterone deficiency associated with a normal or low-normal FSH secretion, and presence of spermatogenesis
Due to the small number of documented cases, it is difficult to determine the true clinical utility of NAC for the treatment of TEN