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Establishment of a novel autoimmune experimental model of bladder pain syndrome/interstitial cystitis in C57BL/6 mice

coli chassis: a pRSF-1 plasmid expressing a ROS-inducible transcription factor OxyR with kanamycin resistance and a pET-19b plasmid expressing a ROS-inducible promoter TrxCp, bifunctional glutathione synthetase, glutathione reductase and glutathione synthetase with ampicillin resistance

Nowadays, EVs, including MSC-derived EVs and EVs derived from other cells, which attenuate ALI mainly by regulating cellular activities such as apoptosis and autophagy, 275 mitochondrial function, and alveolar epithelial-capillary barrier integrity in pulmonary tissues, have been widely applied in animal models of ARDS/ALI

Multiple sclerosis and microbiome