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While the risk of developing PD is reduced with the use of calcium channel blockers to control hypertension, the positive influences of ACE inhibitors, -blockers, and ARBs are not clear (114)

Phase II Clinical Data Jastreboff 2023 (NEJM) reported 24.2% bodyweight reduction at 48 weeks - the largest effect size published for any metabolic peptide in clinical trials
Siegall et al., 1994

Martinez et al., 2018
