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Regulates the bodys metabolism

[3] Glucose-alanine cycle in the liver Once in the liver, hepatic alanine aminotransferase catalyzes a transamination in which alanine, the major gluconeogenic amino acid, acts as an amino group donor, while -ketoglutarate serves as the -keto acid acceptor

The NIH Office of Dietary Supplements, citing Institute of Medicine recommendations, advises that it is advisable for those older than 50 years to meet their RDA mainly by consuming foods fortified with vitamin B12 or a supplement containing vitamin B12. This recommendation reflects the fact that 10 to 30% of older adults lose the ability to efficiently absorb naturally occurring B12 from food

These data indicate CHAC1 is a key regulator of glutathione levels in skeletal muscles, but may not in other organs, likely due to differential tissue expression of Chac1