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2 LS: mechanism and impact Two major criteria are followed to classify individuals with LS, namely, Amsterdam Criteria II and Revised Bethesda Criteria mutations
however, there has been a gradual increase in the incidence of this disease among children and adolescents in recent times [105, 106]
In this case, diverse extracellular stimuli, including cytokines and growth factors, indulge the transcriptional modulation of zinc-associated proteins like ZIPs and ZnTs
Future large-scale, multicenter trials with standardized protocols are essential to validate these findings and facilitate the integration of natural products into mainstream AD treatment frameworks
