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Progressive telomere shortening occurs during cell division due to the inability of the DNA polymerase to synthesize in a 35 direction, leading to the incomplete replication of the lagging strand

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Despite constituting only 2% of total body weight, the brain accounts for approximately 20% of the bodys total oxygen and glucose consumption, underscoring the critical importance of brain energy metabolism as a focal point of scientific research (Blanger et al., 2011)
