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doi: 10.1016/j.cmet.2018.04.010, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 140.Alirezaei M, Kemball CC, Flynn CT, Wood MR, Whitton JL, Kiosses WB
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Methodologically, we advocate species-resolved, compartment-aware assessmente.g., DHE 2-OH-E HPLC for O 2 , targeted HyPer/roGFP-Orp for H 2 O 2 and peroxiredoxin redox stateembedded in composite panels that pair flux with damage footprints and iron/ferroptosis metrics for attribution and trial guidance
When levels run low, skin can look duller and more uneven
