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These include: Lifestyle interventions (dietary advice, physical activity programmes) Licensed pharmacotherapy such as orlistat, or GLP-1 receptor agonists including semaglutide 2.4 mg (Wegovy, NICE TA875) or tirzepatide (Zepbound) where clinically indicated and available Referral to tier 3 or tier 4 weight management services , including bariatric surgery assessment where appropriate Information on NHS weight management services and eligibility for licensed treatments is available via the NHS website and NICE guidance

Long-term human safety data does not exist

Slow IV push: used for lower doses, given over several minutes

Vitamin B12 injections can cause issues with: Leg pain Muscle pain Muscle weakness Swelling in arms and lower extremities Swelling or pain in one leg Unstable walking Neurological Effects The neurological effects of vitamin B12 affect your brain