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Description
Mitochondrial thioredoxin-2/peroxiredoxin-3 system functions in parallel with mitochondrial GSH system in protection against oxidative stress

The main oxidant species involved are H 2 O 2 , ONOOH, NO 2 , HO(X), HO, and O 2

We examined the abundance of F-actin using Phalloidin-Texas Red, a dye that binds to actin-actin interfaces, thereby quantifying only filamentous actin (Figures 7A,B)

This followed a March approval for Rybrevant in combination with chemo for the first-line treatment of locally advanced or metastatic NSCLC with EGFR exon 20 insertion mutations
