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Pacurari M, Kafoury R, Tchounwou PB, Ndebele K

A patient-specific model identifies patients who could benefit from monotherapy and synergistic drug combinations We then employed the model to investigate the utility of monotherapy and combination treatments for individual patients based on the TCGA data

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FIGURE 1 2.3.1 Release of inflammatory mediators and increased oxidative stress In the initial stages of periodontitis, bacterial metabolic products in dental plaque motivate host cells, resulting into the unleashing of various inflammatory mediators