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Hence, with abundant upstream and downstream effectors, targeting NRF2 signaling pathway can effectively affect ferroptosis

10.1097/01.wnf.0000174933.89758.c9 58

3) 0.1 IGF-1: treated with 0.1 g/kg IGF-1 for 10 days (intra-articularly)

Mitochondria-targeted antioxidants protect Friedreich Ataxia fibroblasts from endogenous oxidative stress more effectively than untargeted antioxidants
