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Gamma-glutamyl transferase (GGT), a key liver function biomarker, indicates liver disease and chronic conditions like diabetes and cancer

The endothelium lining the sinusoid walls detects this stretch, further activating endothelial NOS in a positive feedback loop

, Sadamori K., Konishi R., et al

From a translational perspective, targeting oxysterol metabolism and signaling presents both opportunities and challenges
