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Description
The concern about a disulfiram-like reaction that is sometimes cited for nitrofurantoin is a myth: that reaction is caused by metronidazole and certain other antibiotics that inhibit aldehyde dehydrogenase
Research indicates that LPS-activated M1 macrophages suffer from mitochondrial dysfunction (e.g., elevated mROS, calcium overload)
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doi: 10.1007/s10156-009-0007-2
