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For intensity quantification, the z-plane corresponding to the middle of the nuclei was chosen to ensure consistent measurement across samples
doi: 10.1016/j.jnutbio.2011.10.012 9 BerkenboschF.van OersJ.del ReyA.TildersF.BesedovskyH
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This substantial reserve explains why B12 deficiency takes years to develop even when dietary intake ceases
