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Van Mens LJJ, De Jong HM, Fluri I, Nurmohamed MT, Van De Sande MGH, Kok M, Van Kuijk AWR, Baeten D (2019) Achieving remission in psoriatic arthritis by early initiation of TNF inhibition: a double-blind, randomised, placebo-controlled trial of golimumab plus methotrexate versus placebo plus methotrexate

Figure 3 3.2.1 Endothelial damage Endothelial integrity is crucial for maintaining the function of the BBB

1 Introduction Chlorogenic acid (CGA), also called caffeoylquinic acid (CQA), is a dietary polyphenol formed by the esterification of caffeic acid (CA) and quinic acid (QA) ( in vitro , and at 25 M, it reduces reactive oxygen species (ROS) to alleviate oxidative stress in intestinal cells ( eucommia , honeysuckle , and green tea ( The liver is vital for metabolism, the endocrine regulation, and immune response but is often exposed to irritants like viruses, medications, and chemicals ( Building on the aforementioned research findings, we propose the hypothesis that an optimal concentration of CGA confers protection to liver cells via its antioxidant properties

The methylation process is essential for epigenetic gene regulation [35]