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Oxidative post-translational modifications develop LONP1 dysfunction in pressure overload heart failure

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These benefits include supporting healthy detoxification, promoting a healthy immune system, and moderating oxidative stress levels.* It is also essential for brain function, metabolic and biochemical reactions such as DNA synthesis and repair, and is critical in supporting the health of organs such as the lungs and kidneys.* Fun fact: in the body the liver cells can have as much as 10x the amount of active glutathione than other cells

The allosteric activator of PrfA is glutathione (GSH) that is produced by the bacterial glutathione synthase GshF