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Description
This ROS surge, particularly of superoxide anions, rapidly inactivates nitric oxide (NO) and uncouples nitric oxide synthase (eNOS), leading to impaired endotheliumdependent relaxation and increased peripheral resistance [130]

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy

Free radical derivatives formed from cyclooxygenase-catalyzed dihomo-gamma-linolenic acid peroxidation can attenuate colon cancer cell growth and enhance 5-fluorouracils cytotoxicity

Similar to antibodies, one of the applications of EpCAM-specific aptamers is to deliver cytotoxic molecules, such as doxorubicin and neocarzinostatin, to target cells [216]
