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10.1016/j.jalz.2019.04.001 105 VillemagneV
In this reaction, methylene-THF is converted to dihydrofolate (DHF) and then reduced back to THF with the help of dihydrofolate reductase (DHFR) via the folate cycle (Figure 2) [54]
NAD is needed to catalyze over 400 enzymes
B12 ,
