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Description
Chronic excessive intake, particularly when beyond 3 months or at daily doses exceeding 300 g, increases the risk of selenosis (89), whose clinical manifestations may include abdominal symptoms such as vomiting, diarrhea, pain, and nausea as well as a garlic-like odor on the breath (90)

More clinical trials are needed to compare the effectiveness of Colazal to the other mesalamine compounds such as Asacol in treating ulcerative colitis

The Proposed Cytoprotective Principle vs

doi: 10.3389/fnut.2025.1532961
