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Description
Oxidative Stress & Ageing Systemic neutralisation of free radicals that drive premature skin ageing, fine lines, and loss of radiance

Therefore, major treatment approaches for melanin-related lesions now emphasize melano-static therapies

AAD 2015

Conversely, autosomal dominant mutations (classified as CMT2K) generally present a milder, later-onset phenotype, characterized by slowly progressing distal weakness and sensory loss, with maintained ambulation into adulthood [32]
