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High-dose vitamin C (ascorbic acid) therapy in the treatment of patients with advanced cancer
L-Carnitine should be used cautiously or avoided by individuals with seizure disorders, as it may trigger or worsen seizures
Tolerance, adherence, and acceptability of a ketogenic 2.5:1 ratio, nutritionally complete, medium chain triglyceride-containing liquid feed in children and adults with drug-resistant epilepsy following a ketogenic diet

In conclusion, this review outlines that a possible future precision approach to cardiovascular prevention would integrate gut and oral microbiome profiling, LC-MS/MS TMAO quantification, and a selected panel of circulating miRNAs into care pathways, which could trigger individualized interventions (dietprobiotics/berberineperiodontal management) with longitudinal monitoringand would be enabled by assay standardization, multicenter RCTs to define actionable thresholds and identify responders, and EHR-integrated decision support that could drive guideline adoption
