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Alves FM, Kysenius K, Caldow MK, Hardee JP, Crouch PJ, Ayton S, et al

This results in NRF2 accumulation and CDDP resistance [105]

Alternatively, serine can be converted to 3-hydroxypyruvate via transamination of pyruvate catalyzed by alanineglyoxylate and serinepyruvate aminotransferase 2 (encoded by the AGXT2 gene)

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