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Natural or synthetic compounds similar to CR, the so-called CRMs: they have molecular, cellular, biochemical, and physiological effects similar to CR, without dietary restriction, and are a class of chemicals with potential life-prolonging effects that act through different pathways
Over the last decade, the prime concerns for basic, clinical, and demographic research regarding food, diet, supplements, and nutrition in individuals with SCD and thalassemia have been suggested as main areas of research and innovation [167,168]
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Various changes occur in the liver when it develops fatty liver disease
