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Indeed, while in rats exposed to alcohol without BPC 157 administration, more pronounced edema of stroma and striated muscle was seen, in the peptide-treated animals only mild reactive changes on the surface epithelium and scarce, unevenly distributed accumulations of polymorphonuclear inflammatory cells on the muscle were noticed

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It bypasses first-pass hepatic metabolism which oral delivery does not allowing a greater proportion of the absorbed peptide to remain intact as it enters circulation.7 The olfactory pathway also provides a potential direct nose-to-brain route, bypassing the blood-brain barrier a property that has generated interest for neuropeptides and potential neurological applications