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However, the structures of isocereulides E ( 6 ) and F ( 7 ), as well as isocereulide G ( 8 ), which shows another constitutional arrangement of the depsidipeptides D- O -Leu-D-Ala and L- O -Val-L-Val when compared to the isobaric cereulide, violate the canonical NRPS biosynthesis logic as suggested for cereulide production

Certain variants correlate with heightened gastrointestinal sensitivity and slower adaptation to delayed gastric emptying

For transient expression of FOXO1, we transfected cells with pBabe-Puro-FOXO1(de Keizer et al., 2010)