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475,476 PG acts in concert with NO, and the simultaneous inhibition of nitric oxide synthase-2 (NOS2) and COX2 further hinders this process

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10.1074/jbc.RA120.013478 117 NishimuraS.KiokaH.DingS.HakuiH.ShinomiyaH.TanabeK.et al (2025)

The tripeptide backbone consists of three endogenous amino acids (glycine, histidine, lysine), and the copper(II) coordination does not fundamentally alter the metabolic fate of the backbone peptide
