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35 Evidence primarily from preclinical and small human studies indicates that Saccharomyces boulardii can reduce intestinal barrier permeability, suppress Escherichia ( Proteobacteria ) growth, and, with the increase in Bacteroidetes being inconsistent across studies, modulate gut microbiota

Future developments will likely integrate real-time imaging, stimuli-responsive drug release, and personalized biomimetic designs to fully exploit ferroptosis vulnerabilities in clinical translation

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