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This investigation included 212 participants, 107 receiving AD-MSC treatment and 105 receiving a placebo

Panel (b) shows that under stress (e.g., infection, cold, heat, radiation, physical load, emotional stress) an external stress signal activates a cascade of signalling proteins/enzymes including JNK, a stress-activated enzyme that plays important roles in the regulation of a diverse array of cellular functions such as neuronal development, activation of the immune system and programmed cell death (apoptosis)

Indeed, this association between 2-OG, 2-HG and 2-OGDD activity is well substantiated 16,22,24,42,43,44

24.Billou, I., Xu, J., Wildwater, M., Willemsen, V., Paponov, I., Friml, J., Heidstra, R., Aida, M., Palme, K., and Scheres, B
