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Description
This disruption leads to neurological and hematological damage similar to that seen in N 2 O abuse, including posterior column lesions in the cervical and thoracic spinal cord, demyelination, or axonal injury of peripheral nerves
In organisms undergoing catabolism, the E3 ligases Atrogin-1 (also called MAFbx or FBXO32) and MuRF-1 (also called Trim63) are specifically expressed
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At the TGN, it interacts with sorting receptors such as sortilin and carboxypeptidase E for packaging into immature secretory granules (ISGs) [9, 40, 41]
