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Dose Dependent Pharmacokinetics ofN-ACETYLCYSTEINE AFTER ORAL DOSING TO MAN

10.1016/j.drudis.2017.04.010 [DOI] [PubMed] [Google Scholar] 152.N

3 In B12 deficiency, methylmalonic acid (MMA) can accumulate, and it is thought that elevated MMA, alongside elevated homocysteine, contributes to damage of the myelin sheath (which protects nerve cells and speeds up nerve transmission), which can cause irreversible neurological problems
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The controls matched in age, sex, ethnicity, socioeconomic status, geographical region, and calendar year of the first visit documented in LHS records compared to cases
