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The important question of timing of drug treatment has become more high profile in the clinic with the individualization of treatment regimes especially for cancer and the melatonin rhythm might well provide an individual circadian marker for timing specification (201)

Histamine induces peripheral and central hypersensitivity to bladder distension via the histamine H1 receptor and TRPV1

We further tested DeepDIA (detectability prediction trained with HeLa&HEK, MS/MS and RT prediction trained with HeLa1) with detectability prediction on a dataset of four groups (P9, P15, P30, and P54) of mouse tissue samples (Mouse1, see Supplementary Table 1 for details) for cross species validation

These peptides may become more widely accepted, even in light of lack of robust clinical data on safety and efficacy