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In anemia related to vitamin B12 deficiency, an appropriate B12-containing regimensometimes alongside iron or folate when indicatedhelps restore hematologic parameters and reduce neurologic symptoms when instituted promptly and correctly

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B12 injections are needed when the gut cannot absorb dietary B12 properly, or when oral B12 alone is not enough to correct the deficiency

Many patients find that initial tiredness improves as their body adjusts to the medication, typically within the first few weeks of starting treatment