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Description
Polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) gene lead to reduced methylation, elevation of Hcy, reduction of nitric oxide, microvascular disease- particularly capillary endothelial injury and apoptosis, microaneurysms, leakage, ischemia, retinal atrophy, neovascularization, and vision loss [22]
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A cysteine probe with high selectivity and sensitivity promoted by response-assisted electrostatic attraction
Notably, some research has emerged to suggest that ascorbic acid improved endothelial function in diabetic patients (Ashor et al., 1996)