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3-5 days post-op: Local erythema fades, replaced by dark purple bruises 2-4 cm in diameter

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Reduce the starting dose in patients with moderate (Child-Pugh B) hepatic impairment [see Dosage and Administration (2.4), Use in Specific Populations (8.7)]

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Excess nutrient intake, either in the form of carbohydrate or lipid, can result in increased intracellular glucocorticoid activation, especially in adipose tissue and skeletal muscle, both of which are critical insulin-responsive tissues

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