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MOTS-C does not bind a classical cell-surface receptor

21 Heriditary cystatin C amyloid angiopathy (HCCAA): Hereditary cystatin C amyloid angiopathy (HCCAA) is a rare dominantly inherited disease caused by a leucine to glutamine variant of human cystatin C (hCC)

CM-10 has a positive effect when ligated to scaffolds, so perhaps this is the optimal manner in which to use these peptides as free peptides may actually be unstable and easy diluted in vivo

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