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Description
Upon binding cytoplasmic DNA, it recruits RIP2 via its WD40 domain, activating NF-B-mediated inflammation
Functions as a melanocortin receptor agonist with anti-inflammatory properties studied independently of the full -MSH sequence
Kato, T., Kasai, T., Yatsu, S.,
An experimental compound that blocks iron-driven lipid damage rescued cell viability, pointing toward a possible therapeutic target if the finding holds up in animal models and human tissue
