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In addition, there was also a significant reduction in VAS score pain scale, with severe pain reported in 40.2% at baseline to 3.6% at 6 months

The decreased binding of IGF-1 LR3 to IGFBPs may affect its bioavailability and interactions with specific tissues in research settings

ACS Nano 13 , 13651384 (2019)

The stack as a combined injectable formulation is outside the scope of FDA approval
