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Recently the lipid peroxidation product 4-HNE was shown to directly adduct GCLC Cys553 (and GCLM Cys35) in vitro [132]
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United States Patent US8268372 (B2) Orumets K, Kevvai K, Nisamedtinov I, Tamm T, Paalme T (2012) YAP1 over-expression in Saccharomyces cerevisiae enhances glutathione accumulation at its biosynthesis and substrate availability levels
