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Many drugs have been proposed to treat CVS in the acute phase and on a long term to avoid the recurrences of vomiting crisis

Although there are no efficacy data that specifically address longer-term antimanic treatment with Depakote, the safety of Depakote in long-term use is supported by data from record reviews involving approximately 360 patients treated with Depakote for greater than 3 months
625 - 638 Copyright The Authors 2019 Carnitine is a vitamin-like substance that plays a vital role in the -oxidation of long-chain fatty acids (FA) to produce energy by transporting them from the cytosol to the mitochondrial matrix, via carnitine palmitoyltransferase 1 (CPT1) ( Reference Bremer 1 , Reference Zammit, Ramsay and Bonomini 2 )
