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ESRD Patients on Hemodialysis The recommended starting dose is 10 to 20 mg/kg dry body weight as a slow 2 to 3 minute bolus injection into the venous return line after each dialysis session

American Academy of Dermatology

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It is obvious that sometimes, HAs and paraproteins are actually the same clone of immunoglobulins, but paraproteins can be present in all clinical specimens and tissues, whereas HAs are usually absent in urine [1161,1166]