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It was suggested that IFN- secreted by T cells can trigger LPO of tumor cells

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Notably, while neuronal elements (axons, neurons, dendrites, and synapses) are also damaged to a significant extent (Mck et al., 2021), demyelination is a constant finding in both white and gray matter regions pointing to the myelinating unit (the myelin sheath and oligodendrocyte) as a key target in this disease