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Since EDS-related motility issues impact both structure and functioning of the MMC, SIBO for these clients often requires long-term management with prokinetics, dietary strategies, and periods of reducing the bacteria and archaea that may continuously overgrow

5 Mechanistic studies indicate that anthocyanins and/or their metabolites can be detected in brain tissue in experimental settings, and that anthocyanins have been reported to cross the bloodbrain barrier, although the extent and physiological relevance in humans remain active research areas

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For patients with autoimmune diseases, using allogeneic CAR T cells may also reduce treatment-related side effects, such as CRS (200, 201)
