glutathione s transferase drug resistance Glutathione-S-Transferases as Potential Targets for Modulation of Nitric Oxide-Mediated Vasodilation The Relationship of Glutathione-S-Transferase and
Description
The mechanistic basis involves RT-induced mitochondrial copper accumulation through coordinated upregulation of CTR1 transporter and depletion of mitochondrial GSH, ultimately initiating cuproptosis

Under disulfide stress, the reductive capacity of the oxidized form of Trx (Trx-S 2 ) is reduced

Cysteine and hydrogen sulphide in the regulation of metabolism: Insights from genetics and pharmacology

Cancer 88 , 951956 (2003)
